Medical Management and Treatment Guidelines

Our goal is to share national and local guidelines and protocols to help you provide high-quality viral hepatitis, HIV, and sexually transmitted infection (STI) prevention and treatment care to your patients.

Viral Hepatitis

For the most current management and treatment guidelines, refer to the clinician resources at Hep Free Hawaii


Pre-Exposure Prophylaxis (PrEP) information 

The U.S. Department of Health and Human Services (DHHS) issues guidance documents for the medical management of HIV infection, including guidelines on antiretroviral treatment, prevention and treatment of opportunistic infections, post-exposure prophylaxis, and preventing perinatal transmission.

Other resources include:

National HIV Telephone Consultation Service
Offers physicians and other health care providers up-to-the-minute HIV clinical information, and individualized expert case consultation across the broad range of clinical HIV/AIDS issues.
Phone: 1-800-933-3413
Hours: 6am–5pm (PST), M–F

National Clinicians’ Post-Exposure Prophylaxis Hotline (PEPline)
Offers clinicians up-to-the-minute advice on managing occupational exposures (i. e., needlesticks, splashes, etc.) to HIV, hepatitis, and other blood-borne pathogens.
Phone: 1-888-448-4911
Hours: 24 hours / 7 days a week

Additional local information on HIV Medical Case Management and Medication Services

Sexually Transmitted Infections (STIs)


Hawaii STD Screening Recommendations, 2015

CDC Laboratory recommendations for detecting Chlamydia trachomatis and Neisseria gonorrhoeae, 2014


Hawaii STD Treatment Guidelines, 2015

CDC STD Treatment Guidelines, 2015

Download the free CDC STD Tx Guide app available for Apple devices and Android devices

Evaluation and Management

Hawaii DOH Guidelines for Neisseria gonorrhea Infection Treatment, Management, and Reporting, 2011

Evaluating Patients for Primary Syphilis

Evaluating Patients for Secondary Syphilis

Expedited Partner Therapy (EPT)

EPT is the clinical practice of treating the sexual partners of a patient diagnosed with a sexually-transmitted infection (STI) by having the patient convey medication or a prescription to his or her partners. Hawaii’s EPT law allows health care providers to offer this treatment to partners of their patients without medical examination of those partners.

EPT is not recommended as a first-line response to diagnosis of a treatable STI in patients.  While the most effective treatment of patients’ infections will include proper treatment of their recent and current sexual partners, the best practice is for partners of medically evaluated patients to obtain prompt medical evaluation themselves. This is important for ensuring good health in the partners, preventing reinfection of the patient already diagnosed and treated, and reducing the further spread of unrecognized infections in our community.

The Hawaii law permits EPT treatment for all conditions recommended for EPT treatment by the Centers for Disease Control and Prevention (CDC). CDC EPT recommendations and treatment guidelines are available online.

Partner Information Sheets

Chlamydia infection

Gonorrhea infection

Chlamydia and gonorrhea infection