• Double vision
• Blurred vision
• Drooping eyelids
• Slurred speech
• Difficulty swallowing
• Dry mouth and
• Muscle weakness

Infant botulism is caused by ingestion of spores of the botulinum bacterium which grow in the intestine and release toxin that has its main effect on the nervous system. Botulism spores are quite common and are found in foods such as honey.

Food-borne botulism results from eating the pre-formed toxin (toxin made by the bacteria in contaminated food). The bacteria are most commonly found in poorly preserved, often home-canned or home-bottled food items. Cooking food well will inactivate the toxin.

Wound botulism is rare and is caused by botulism bacteria infecting a wound and making the toxin. Botulism is not spread from person to person.

Botulism is not spread from one person to another. Foodborne botulism can occur in all age groups.

Botulism is a rare disease and diagnosis may be blurred by other similar disease such as Guillain-Barre syndrome, stroke and myasthenia gravis. Diagnosis by clinical symptoms should be done along with laboratory test demonstration of the presence toxin in the patient’s serum or feces or the food the patient has consumed. The most sensitive method of testing is the mouse neutralization assay.

Medical treatment is available for persons with botulism. Treatment may include antitoxin and breathing machine to prevent respiratory failure. Antitoxin medicines block the effects of the toxin circulating in the blood. The effects of the toxin may take weeks to months to wear off. An antitoxin for infant botulism is also available and should be administered as early as possible. Antitoxin is available from the Centers for Disease Control and Prevention (CDC).

There is currently no medicine to prevent botulism. There is an investigational vaccine that is available only to laboratory personnel working with Clostridium botulinum or the toxin.

Risk of acquiring botulism can occur from ingesting of the bacterial toxin and from infected wounds. The bacteria that causes the disease can be found in soil, dust, inside homes on the floors, carpet and countertops. Foodborne botulisms have often been from improper home canning methods.

Foodborne botulism can be prevented with good food safety practices;

• Be very careful when canning foods at home to reduce contamination of foods. Follow instructions on safe home canning as recommended by the US Department of Agriculture in the  USDA Complete Guide to Home Canning.
• Keep oils infused with herbs or garlics in the refrigerator and discard after 4 days.
• Do not purchase products that appear to have thawed and refrozen, canned goods that appear swollen or spoiled.
• Observe any use-by or sell-by dates on packaged foods.
• Keep baked potatoes that have been wrapped in aluminum foil at temperatures above 140° F until served.
• Children younger than 12 months should not be fed honey.

Wound botulism can be prevented by immediately cleaning any wounds and keeping them clean.  If wounds appear infected (swollen, red, painful, discharge or pus, fever or warm to touch); seek prompt medical care.

USDA Complete Guide to Home Canning

U.S. Government Food Safety

Centers for Disease Control and Prevention (CDC)

Bad Bug Book (Second Edition), FDA

Hawaii State Department of Health Botulism Fact Sheet (PDF)

Hawaii State Department of Health Botulism Bioterrorism Brochure (PDF)

Wound or infant botulism is a reportable disease Hawaii Administrative Rules Title 11 Chapter 156, Communicable Diseases, under the Routine category which requires a report by telephone, fax or mail to the Disease Outbreak Control Division on Oahu or to the District Health Offices on the neighbor islands. A written Communicable Disease Report (CDR) may be submitted by mail or fax.

For additional diagnosis and treatment information, the patients physician should consult with the Centers for Disease Control and Prevention (CDC)  and the Infant Botulism Treatment and Prevention Program (IBTPP) for infants.

Last reviewed July 2019